Purpura Hæmorrhagica: Splenectomy

Treatment of Purpura Hæmorrhagica

A Case for Diagnosis: (? Variola or Purpura Hæmorrhagica)

PURPURA HEMORRHAGICA). To the Editor, The Indian Medical Gazette. Sir,?On the 14th June, 1927, I was called in to attend a Hindu boy, aged about 13 years, whom I found to be unconscious, with a temperature of 103.4?F., and with constipation of two days' standing. I wasft told that prior to this illness, the boy had always been healthy. The day before he had been apparently in perfect health, ta...

Splenectomy in relapsing and plasma-refractory acquired thrombotic thrombocytopenic purpura.

BACKGROUND AND OBJECTIVES Acquired thrombotic thrombocytopenic purpura (TTP) is often due to autoantibodies inhibiting ADAMTS-13 activity resulting in impaired processing of very large von Willebrand factor multimers. TTP usually presents with an acute onset and a fulminant, sometimes fatal course. With appropriate treatment including plasma exchange, and fresh frozen plasma replacement, often ...

Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy

Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphos...

Late Results After Splenectomy in Adult Idiopathic Thrombocytopenic Purpura

BACKGROUND We performed a retrospective study on patients with idiopathic thrombocytopenic purpura (ITP) to evaluate the response to splenectomy in relation to preoperative platelet count. MATERIALS AND METHODS Two groups of patients operated on with laparoscopic or open splenectomy for ITP, with a platelet count ≤30,000/μL (study group: 22 patients) and >30,000/μL (control group: 18 patients...